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(Other research supports this idea, showing that receptors for dopamine, a neurotransmitter, are altered in people with high amounts of fat tissue.) This persistent biological hunger continued even when people lost weight, adding another challenge to maintaining a healthy weight

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Biochem Soc Trans 34:5558 Blair IA (2006) Endogenous glutathione adducts

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1 Introduction Obesity is a chronic, multifactorial, and progressive disease associated with type 2 diabetes mellitus, hypertension, cardiovascular disease, and several cancers (Phelps et al., 2024